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As oxidative stress plays a crucial role in the amphetamines-induced neurotoxicity (Moratalla et al., 2017), the above and the present results suggest that AT 1 -R may be involved in neurotoxicity effects of others amphetamines derivatives such as 3,4-methylenedioxymethamphetamine

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After exposing the right knee femoral condyle with a medial para-patellar incision, cartilage was removed using a surgical blade from the trochlear surface